A Pump For By-Passing the Right Heart of Dogs- William Sewell (1950) A Thesis

Description

This thesis was presented to the faculty of the Yale University School of Medicine in candidacy for the Degree of Doctor of Medicine in 1950 by William H. Sewell, Jr.. Dr. Sewell went on to become a very important doctor. This is a one of a kind copy of his thesis. It is a self-published typed work. The pictures in it were actually glued in. The title of the work Was "A Pump For By Passing The Right Heart of Dogs". The book is in VG condition.
After a number of acute experiments on dogs to work out procedural details and to ascertain that there were no forbidding physiologic or biologic obstacles to right heart bypass, two long-term survival experiments were carried out with all the preparations that we applied to a clinical operation and its post-operative management. Total bypass of the right side of heart for 61 and for 82 minutes was accomplished, with the right ventricle widely open during most of this time. After restoration of the normal circulation, removal of the pump, and closure of the chest, the dogs made an uneventful recovery. Sometime later an elective autopsy revealed no pathologic abnormalities related to the operation. That it was possible to bypass one side of the heart with a mechanical pump for a prolonged period with survival of the animal and that the chamber of the right ventricle could be exposed long enough for deliberate performance of a cardiac operation under visual control had been demonstrated. A preliminary report of these experiments was made at the Surgical Forum of the American College of Surgeons in 1949, and a more formal report followed in Surgery in 1950. (B4)